Located just steps from the famous Magnificent Mile shopping district in River North, contemporary art surrounds and inspires you at 21c Museum Hotel Chicago. Discover a new kind of cultural and travel experience in the Windy City with this multi-venue museum and 297 room boutique hotel featuring 106 suites.
*As of November 4, 2025, 21c Chicago will no longer operate as a 21c Museum Hotel branded property. 21c Chicago will transition to a new brand, the Tribute Portfolio by Marriott, managed by Coury Hospitality. Questions regarding upcoming reservations made at this property should be directed to the hotel at (312) 660-6100.
Rooms & Suites
Step into a stylish retreat in the heart of Chicago, where light-filled rooms, contemporary design, and original artwork create an unforgettable stay. Sink into plush bedding, indulge in spa-like Malin+Goetz amenities, and enjoy modern comforts like free Wi-Fi and 43” HDTVs—just steps from the energy of the Magnificent Mile.
Celebrate in an environment that simultaneously reflects global contemporary culture and Chicago’s unique perspective. 21c Chicago’s expansive and art-filled event spaces were made to inspire creative gatherings ranging from 10 to 300 people.
D (US) T is a collection of work by Daniel Hojnacki that contemplates the temporality of the body and its intrinsic interconnectedness with the cosmic landscape.
Truth or Dare: A Reality Show
Highlighting uncertainty and contradiction, the artworks featured in Truth or Dare: A Reality Show emphasize the importance of questioning both knowledge and belief by utilizing illusion to entice, entertain, and explore the terrain between fact and fiction, presence and absence, reality and imagination. The suspension of disbelief is invoked in works that simulate games, maps, and tricks…
Rm 921: Willea Zwey
Projected onto a 48-foot wall, Et Sic Videmus is only viewable after dusk and from the windows of 21c Chicago guest rooms with interior-facing windows. Designed to showcase immersive and experiential moving-image work in response to the unique space, Elevate: Rm 921 addresses complex issues that shape our diverse and rapidly changing world.
Dine & Drink
A sleek, sophisticated spot where top-tier seafood, prime steaks, award-winning burgers, and craft cocktails meet the energy of River North.
Lure Fishbar
Lure Fishbar is Chicago’s most compelling destination for world-class seafood and sushi, premium steaks, burgers, and much more. With timeless elegance and buzzing energy, Lure offers the perfect night out in River North.
