Located in the heart of downtown St. Louis, this 173-room boutique hotel houses a contemporary art museum, the Idol Wolf restaurant, the Good Press café, and the Locust Street Athletic and Swim Club, a full-service wellness center.
Rooms & Suites
Where historic architecture meets contemporary comfort—explore art-filled rooms and suites designed for rest, inspiration, and discovery.
Bunk RoomDeluxe KingDeluxe Double QueenLuxury Double QueenCorner KingDeluxe King SuiteLoft Double QueenCorner King SuiteLibrary King SuiteLuxury King Suite21c King Suite
Offers
Looking for more than just an ordinary hotel stay? Discover your ideal St. Louis retreat at 21c Museum Hotel.
Superheroes and celebrities, totems and toys: the imagery of manufactured fantasy is reframed in the visual language of historical iconography in this multi-media exploration of popular culture today.
O
Serkan Ӧzkaya’s O, imagined in the ephemeral form of a giant bubble, playfully asks the question: How do you really know where you are, or what is real?
Until We Meet Again
Until We Meet Again is A Facility Artwork created by Nick Cave and Bob Faust for 21c Museum Hotel St. Louis.
View Finder
Celebrating the streetscape and historic architecture of St. Louis, Chandler Ahrens’s View Finder is a faceted, gem-like installation inspired by 17th-century catoptric viewing boxes.
The Way Out West
Created for 21c Museum Hotel St. Louis, The Way Out West is an immersive artwork installation for the historic stairwell that connects the public spaces and art galleries.
Dine & Drink
Dine with art at 21c St. Louis, where Idol Wolf’s playful approach to tapas blends local ingredients with Iberian traditions, and Good Press offers a vibrant café experience featuring the best of St. Louis coffee culture.
idol wolf
Inspired by the rich culinary traditions of Spain, Idol Wolf takes a playful approach to tapas style dining by combining local and seasonal ingredients with classic Iberian sensibilities. The menus blend Spanish classics with a distinctly Midwestern point of view – the result is a shared drinking and dining experience that is truly memorable.
Serving as a welcoming communal meeting place for hotel guests and downtown residents alike, Good Press is committed to always putting the best of what St. Louis has to offer front and center. Whether guests are dropping in for a quick fuel up in the morning or setting up shop for the afternoon, they’ll always be able to find great coffee, deliciously simple food, and the ambient buzz of community.
Meetings, events, and gatherings for those looking for something spectacular. When hosting corporate conferences, cocktail parties, or anything else in between, 21c ensures crafted creativity down to the last detail.
Immersed within a historic St. Louis building that once thrived as a recreational haven, Locust Street Athletic and Swim Club proudly honors its origins while redefining the very essence of fitness and wellness.
Spa
Unwind and recharge with one of our massage treatments. Our menu was designed to help members reduce stress, recover faster from workouts, and leave feeling relaxed. Book your treatment and elevate your massage with one of our add-ons.
Located in a historic building in St. Louis once used as a YMCA, Locust Street Athletic and Swim Club pays homage to its roots and reimagines the meaning of fitness and wellness. With personal and group training, swim lessons, and spa services, we offer members and guests a modernized approach to traditional methods of movement and recovery.
At 21c St. Louis, we foster innovation and collaboration, sparking change and thought-provoking conversations. Committed to utilizing the city’s infrastructure and vibrant community, we create a safe, inclusive environment centered around art, culture, and community engagement through programming, events, and monthly giveback partnerships.
