Art-filled escape in the heart
of Louisville.

Rooms

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Dine & Drink

Proof on Main is a culinary love-letter to the Ohio River Valley, led by Kentucky native and Executive Chef Cody Stone.

proof on main

One of Louisville’s most iconic dining institutions, Proof on Main’s menus showcase a unique and well-traveled approach to southern and Appalachian-inspired cuisine. The Proof on Main lounge is also home to the 21c Selects Private Barrel Program, and is consistently ranked one of the best bourbon bars in the country.

Meetings & Events

Gatherings for those looking for something spectacular. When hosting corporate conferences, cocktail parties, or anything else in between, 21c ensures crafted creativity down to the last detail.

21c Louisville event space set up for an event with furniture, floral arrangements and ambience lighting

FIND US

21c Museum Hotel Louisville
700 W Main Street
Louisville, Kentucky 40202

Phone (502) 217-6300